TABLE 1

Designation of metabolites

PXyMetabolite of C-1311
P*XyMetabolite of C-1330
XNumber of HPLC peaks related to metabolites obtained in the given enzymatic system
yType of metabolite system
PXRName of metabolite found with rat liver microsomes
PXHName of metabolite found with human liver microsomes
PXFMOName of metabolite found with human FMOs
PXUGTName of metabolite found with human UGTs