Summary of individual human jejunal microsome preparations
| Donora | Gender | Age | CYP3A Activity ± S.D.b |
|---|---|---|---|
| yr | nmol · min−1 · mg−1 | ||
| HJM 1 | Male | 24 | 2.09 ± 0.176 |
| HJM 2 | Male | 59 | 3.08 ± 0.085 |
| HJM 3 | Male | 26 | 2.63 ± 0.151 |
| HJM 4 | Male | 35 | 3.38 ± 0.485 |
| HJM 5 | Male | 68 | 5.15 ± 0.313 |
| HJM 6 | Male | 60 | 5.56 ± 0.122 |
| HJM 7 | Female | 39 | 5.20 ± 0.198 |
| HJM 8 | Female | 65 | 5.88 ± 0.393 |
a Microsome preparation by elution method from the jejunum.
b Testosterone 6β-hydroxylation activity was determined at a testosterone concentration of 250 μM.