Percentage of cumulative radioactivity recovered from six healthy male and female subjects after a single 250-mg oral suspension dose of [14C]lapatinib
Median data are shown because of variability in recovery of total radioactivity.
| Time Period | Feces | Urine | Total |
|---|---|---|---|
| % dose | |||
| 0–24 h | 10.5 | 1.01 | |
| 0–48 h | 45.3 | 1.16 | |
| 0–72 h | 74.9 | 1.16 | |
| 0–96 h | 78.4 | 1.16 | |
| 0–120 h | 90.8 | 1.16 | |
| 0–144 h | 91.4 | 1.16 | |
| 0–168 h | 91.8 | 1.16 | 93.1 |