Modeling the depletion-time profiles for the conventional and media-loss methods at 0.1 μM initial substrate concentrations
| Compound | CLmet | CLuptake | Pdiff | Vcell | Vmedium |
|---|---|---|---|---|---|
| μl · min−1 · 106 cells−1 | μl/106 cells | μl | |||
| Atorvastatin | 77.4 ± 5.1 | 393 ± 576 | 234 ± 303 | 2164 ± 370 | 198 ± 29 |
| Fexofenadine | 13.5 ± 2.2 | 115 ± 136 | 42.6 ± 23.6 | 912 ± 384 | 221 ± 25 |
| Pitavastatin | 7.2 ± 3.7 | 716 ± 255 | 162 ± 21 | 555 ± 185 | 211 ± 29 |
| Rosuvastatin | 3.1 ± 1.2 | 627 ± 236 | 190 ± 24 | 192 ± 22 | 186 ± 37 |