TABLE 2

Glucuronidation assays conditions

The selected substrates that were used for each recombinant UGT, the substrates and protein concentrations in the incubation, and the inclusion of DMSO in some of the assays are listed.

EnzymeSubstrate[S]DMSO[Protein]
μM%mg/ml
UGT1A11-Naphthol100No0.05
4-MU100No0.05