TABLE 1

Laboratory variables during hemorrhagic-shock resuscitation by rHSA, RBCs, or CO-RBCs

Values are means ± S.D. (n = 6–8).

VariablepHPaO2PaCO2BELacHbCO
TorrTorrmmol/lmmol/l%
Before hemorrhage
 RHSA7.35 ± 0.0375.8 ± 4.439.1 ± 4.21.1 ± 1.30.7 ± 0.1ND
 RBC7.35 ± 0.0276.7 ± 3.739.3 ± 3.11.7 ± 0.70.7 ± 0.1ND
 CO-RBC7.36 ± 0.0574.3 ± 3.540.7 ± 7.81.0 ± 1.70.7 ± 0.2ND
After hemorrhage (0 min)
 RHSA7.22 ± 0.08*102.1 ± 11.3**24.8 ± 6.8**−4.3 ± 1.6**4.2 ± 1.1**ND
 RBC7.21 ± 0.03*101.8 ± 9.2**24.7 ± 8.3**−5.3 ± 2.1**4.4 ± 1.3**ND
 CO-RBC7.21 ± 0.08*100.0 ± 10.1**26.7 ± 4.5**−3.7 ± 0.6**4.1 ± 1.1**26.4 ± 6.6
After hemorrhage (60 min)
 RHSA7.21 ± 0.03*84.7 ± 8.233.4 ± 4.90.6 ± 1.10.7 ± 0.2ND
 RBC7.21 ± 0.01*78.5 ± 6.138.3 ± 6.10.7 ± 0.60.9 ± 0.1ND
 CO-RBC7.20 ± 0.07*75.3 ± 2.440.3 ± 4.71.7 ± 1.00.8 ± 0.13.2 ± 5.0
  • BE, base excess; HbCO, Carbonyl hemoglobin; Lac, lactate; ND, not determined.

  • * P < 0.05 vs. baseline.

  • ** P < 0.01 vs. baseline.