TABLE 1

Known functional alterations in the Oat3-knockout kidney

MoleculeClassReference
MethotrexateDrugVanWert and Sweet, 2008
Penicillin GDrugVanWert et al., 2007
FurosemideDrugVallon et al., 2008b
BendroflumethiazideDrugVallon et al., 2008b
CiprofloxacinDrugVanWert et al., 2007
UrateMetaboliteEraly et al., 2008
Ro 64-0802 (active form of oseltamivir)DrugOse et al., 2009
Aristolochic acidToxinXue et al., 2011
ZidovudineDrugNagle et al., 2011
AcyclovirDrugNagle et al., 2011
TenofovirDrugNagle et al., 2011
LamivudineDrugNagle et al., 2011
CreatinineMetaboliteVallon et al., 2012