Scaling parameters to calculate CLint or CLh
| Model | HepatoPac | Suspended Hepatocytes |
|---|---|---|
| Maximum incubation time, h (min) | 168 (10,080) | 6 (360) |
| Hepatocytes per well | 5000 | 50,000 |
| Incubation volume (ยตl) | 64 | 50 |
| In vivo (hepatocyte), (n per g liver) | 120,000,000 | |
| Liver weight (g) | 1800 | |
| Average body weight (kg) | 70 | |
| Liver blood flow (ml/min per kg) | 21 | |