In vitro intrinsic clearance in HLM after incubation with ethanol or d6-ethanol
| Conditions | In Vitro Intrinsic Clearance | |||
|---|---|---|---|---|
| Ethanol | d6-Ethanol | CDP323 Consumption | Formation of CT7758 | Formation of Transester d5-CDP323 |
| % | % | µl/min/mg protein | ||
| 0 | 0 | 206 | 177 | NA |
| 0.5 | 0 | 140 | 126 | NA |
| 0 | 0.5 | 231 | 123 | 81.1 |
NA, not applicable.