Percentage of circulating tofacitinib and metabolites in plasma following a single oral dose of 14C-tofacitinib 50 mg (n=6)
| Analyte | Tofacitinib | M1/M2 | M4 | M9 | M11/M20/M29 | M14 |
|---|---|---|---|---|---|---|
| Mean (S.D.) % of total circulating activity | 69.4 (8.5) | 7.4 (3.6) | 3.9 (1.6) | 1.0 (0.5) | 6.2 (1.4) | 3.2 (2.1) |