TABLE 1

Demographics for hepatocyte donors used in the HepatoPac model to study protein interactions

Demographics	Donor 1	Donor 2	Donor 3^{^a}	Donor 4^{^b}
Gender	Female	Male	Female	Female
Age	19	56	54	61
Race/Ethnicity	Caucasian	African American	Caucasian	Not provided
Cause of Death	Intracerebral bleed secondary to ICH/stroke	CVA	Anoxia secondary to CVA	Not provided
Medical History	Lupus	Diabetes, hypertension, kidney disease, insulin	Diabetes and hypertension, 3 years, medicine compliant	Not provided
Social History	No alcohol, tobacco, or drug use	No alcohol, tobacco, or drug use	Nonsmoker, social drinker	Not provided

CVA, cerebrovascular accident; ICH, intracerebral hemorrhage.
↵^a This donor was determined through genotyping analysis to be organic anion-transporting polypeptide (OATP) wild type and CYP3A5 *3*3
(Ramsden et al., 2014a).
↵^b Donor ID “RTM” from the manufacturer.