Observed and predicted ibuprofen pharmacokinetic parameters at steady state
Steady-state (ss) values obtained via Aarons et al. (1983a).
| Parameter | Observed Value Mean (% CV) | Predicted Value Mean (% CV) | Observed/Predicted |
|---|---|---|---|
| Tmax,ss (hour) | 1.3 (14) | 1.3 (19.5) | 1.05 |
| Cmax,ss (µg/ml) | 29.7 (19) | 28.0 (22.7) | 1.06 |
| AUCss (µg/ml per hour) | 108.1 (12.3) | 119.6 (35.3) | 0.90 |