TABLE 1

Cytotoxic drugs studied in this study and their indications

DrugMajor Indication
DoxorubicinLymphomas
Breast cancer
Sarcomas
Hepatocellular cancer
Leukaemias
EpirubicinBreast cancer
Hepatocellular cancer
DaunorubicinAcute myelogenous leukemia
Acute lymphocytic leukemia
IdarubicinAcute myelogenous leukemia
EtoposideTesticular cancer
Small cell lung cancer
Ovarian cancer
Irinotecan (SN-38)Colorectal cancer
Pancreatic cancer
Ovarian cancer
TopotecanSmall cell lung cancer
Ovarian cancer
Lung cancer
5-FUColorectal cancer
Breast cancer
Ovarian cancer
Hepatocellular cancer
Stomach cancer
Pancreatic cancer
CamptothecinNot approved for clinical use
Mitomycin CHepatocellular cancer
Stomach cancer
Pancreatic cancer
Colon cancer
Breast cancer
Anal cancer
Lung cancer