Single Intravenous Infusion (50 mg) | Single Oral Administration (250 mg) | |||||
---|---|---|---|---|---|---|
Cmax | AUC0–∞ | t1/2 | Cmax | AUC0–∞ | t1/2 | |
ng/ml | ng⋅h/ml | h | ng/ml | ng⋅h/ml | h | |
Observed | 155 (19) | 1067 (18) | 39 (16) | 100 (28) | 2321 (34) | 29 (10) |
Predicted | 167 (11) | 1258 (23) | 45 (19) | 103 (34) | 2878 (47) | 58 (24) |
P/Oa | 1.1 | 1.2 | 1.2 | 1.0 | 1.2 | 2.0 |
↵a Ratio of the predicted to observed results.