Pharmacokinetic parameters of deleobuvir and CD 6168 in plasma after oral administration of 10 mg/kg deleobuvir to control and pGF rats
| Group | Analyte | tmax | t1/2 | Cmax | AUC0-∞ |
|---|---|---|---|---|---|
| hours | hours | ng/ml | ng·h/ml | ||
| Control | Deleobuvir | 1 | 4a | 15,784 ± 4,533 | 63,438 ± 18,181 |
| pGF | 1 | 5 ± 1 | 18,718 ± 9,840 | 66,683 ± 21,253 | |
| Control | CD 6168 | 6–8b | N.D. | 114 ± 65 | 1,312 ± 649 |
| pGF | N.D. | N.D. | 15.5 ± 7.7 | 146 ± 64 |