List of genes that are differentially regulated at the transcription level by the presence of intestinal bacteria
| Decreased in GF Mice | Increased in GF Mice |
|---|---|
| Phase-1 drug-metabolizing enzymes | |
| Ces2a | Ces1g |
| Ces3b | Akr1c20 |
| Ces4a | Akr1d1 |
| Akr1c19 | Aldh3a2 |
| Aldh1b1 | Fmo2,5 |
| Aox1 | Cyp1a2 |
| Cyp2b10 | Cyp2a5,22 |
| Cyp3a11,16,44,59 | Cyp2b9 |
| Cyp4f17 | Cyp2c38,39,40,50,54,67,68,69 |
| Cyp4a10,12b,14,31,32 | |
| Phase-2 drug-metabolizing enzymes | |
| Gsta1 | Gstt2,3 |
| Gstp1,2 | Sult1a1 |
| Gstm3 | Sult1b1 |
| Ugt2b35,37,38 | Sult1d1 |
| Sult5a1 | |
| Transporters | |
| Asbt | Ntcp |
| Oatp1b2 | |
| Ent1 | |
| Mrp2 | |
| Abcg5 | |
| Abcg8 |
Asbt, apical sodium dependent bile acid transporter; Ent1, equilibrative nucleoside transporter 1.