Retention time of parent drug and its corresponding acyl glucuronide metabolites
| Test Compound | Retention Time (Min) of Metabolites Detected | |||||
|---|---|---|---|---|---|---|
| M0 | 1-O-β-AG | Isomer-01 | Isomer-02 | Isomer-03 | Isomer-04 | |
| Valproic acid | 8.21 | 11.39 | 11.68 | — | — | — |
| Gemfibrozil | 17.10 | 5.22 | 6.76 | 7.15 | — | — |
| Telmisartan | 6.06 | 5.98 | 6.47 | 7.00 | — | — |
| Montelukast | 12.00 | 4.81 | 3.07 | — | — | — |
| Meclofenamate | 8.18 | 4.35 | 4.96 | 5.78 | — | — |
| Mefenamic acid | 7.28 | 3.84 | 5.12 | — | — | — |
| Levofloxacin | 12.20 | — | — | — | — | — |
| Repaglinide | 5.78 | 4.02 | 4.54 | — | — | — |
| Clofibric acid | 10.10 | 14.84 | 16.59 | 17.12 | — | — |
| Flufenamic acid | 8.14 | 4.48 | 5.22 | 5.80 | 6.33 | 6.74 |
| Furosemide | 7.52 | 6.88 | — | — | — | — |
| Ibuprofen | 10.30 | 9.51 | 9.94 | 10.66 | 10.94 | 11.27 |
| S-Naproxen | 8.56 | 11.48 | 12.93 | 13.30 | 13.70 | — |
| Indomethacin | 9.97 | 9.78 | 11.24 | 11.54 | — | — |
| R-naproxen | 8.64 | 11.67 | 9.82 | 12.75 | 13.37 | — |
| (RS)-Benoxaprofen | 12.20 | 4.35 | 4.96 | 5.78 | — | — |
| Dabigatran | 8.63 | — | — | — | — | — |
| Ibufenac | 8.14 | 8.42 | 9.51 | 9.9 | — | — |
| Diclofenac | 8.58 | 9.73 | 4.04 | 6.2 | 7.79 | — |
| Diflunisal | 13.9 | 1.90 | 7.67 | 10.91 | 11.93 | 13.05 |
| Tolmetin | 8.98 | 11.07 | 7.09 | 10.05 | 11.90 | 13.01 |
| Zomepirac | 8.27 | 9.73 | 6.52 | 8.71 | 10.39 | 11.17 |
| Probenecid | 7.38 | 4.58 | 7.42 | 7.94 | 9.07 | — |