Examples of possible endogenous biomarkers of CYP2D6 activity
| Biomarker |
|---|
| 14,15-Epoxyeicosatetraenoic acid ethanolamide |
| 20-Hydroxyeicosatetraenoic acid ethanolamide (20-HETE ethanolamide) |
| 5-Methoxy-N,N-dimethyltryptamine (5-MDMT) |
| 5-Methoxytryptamine (5-MT) |
| 6-Hydroxy-1,2,3,4-tetrahydro-β-carboline |
| 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (pinoline) |
| Bufotenine |
| N-Arachidonylethanolamine (anandamide) |
| Serotonin (5-HT) |
These data are from Yu et al. (2003a,b), Snider et al. (2008), Preskorn et al. (2009), and Sridar et al. (2011).