Highest fold induction of DPGs among neonatal (days 2 and 5), adolescent (day 25) and adult (day 60) ages
| Age | Ligand (Xeno-Sensor) | DPG |
|---|---|---|
| Neonatal (days 2 and 5) | TCDD (AhR) | Cyp1a2, Sult5a1, Ugt1a9 |
| TCPOBOP (CAR) | Cyp3a11, Mrp2 | |
| PCN (PXR) | Gstm2, Gstm3 | |
| Adolescent (day 25) | TCDD (AhR) | Ugt1a6, Mrp4 |
| TCPOBOP (CAR) | Cyp2b10, Ugt2b34, Ugt2b35 | |
| PCN (PXR) | Gsta1, Gsta4, Sult1e1, Ugt1a1, Mrp3, Mrp4 | |
| Adult (day 60) | TCPOBOP (CAR) | Aldh1a1, Aldh1a7, Ugt2b36 |
| PCN (PXR) | Papss2, Oatp1a4 |