Tissue sample donor demographics
To ensure good age representation and adequate power, target sample sizes for birth to 30 days, greater than 30 days to 1 year, greater than 1–5 years, greater than 5–10 years, and greater than 10–18 years age brackets were developed based on data from the existing literature on drug and toxicant metabolizing enzyme ontogeny. Samples sizes were sufficient to provide at least 80% power to detect a 1 S.D. change in enzyme specific content between age brackets assuming α = 0.05.
Variable | Median | Range | |
---|---|---|---|
Age at death (mo) | 3.7 | 0–212 | |
Postmortem interval (h) | 17 | 1–41 | |
No. | % of Total | ||
Hepatic tissue samples | 165 | 100 | |
Sex | Male | 104 | 63 |
Female | 58 | 35 | |
Unknown | 3 | 2 | |
Ethnicity/race | Northern European white | 79 | 48 |
African American | 62 | 38 | |
Hispanic | 16 | 10 | |
Asian | 2 | 1 | |
Native American | 1 | <1 | |
Unknown | 5 | 3 |