Physiologic volumes and blood flows used for modeling and simulation of rat data
Blood Volume | Value | Blood Flow | Value |
---|---|---|---|
ml | ml⋅min−1 | ||
Total blood volume (VB)a | 16.2 | Hepatic artery (QHA)g | 3.94 |
Intestinal blood volume (VIB)b | 1.5 | Portal vein (QI)g | 11.7 |
Serosal blood (Vser,B) = fQ * VIB | —^ | g | |
Enterocyte blood (Ven,B) = (1 − fQ) * VIB | — | Rapidly perfused tissue (QHP)f | 33.3 |
Intestinal tissue (VI)c | 2.2 | Poorly perfused tissue (QPP)f | 20.4 |
Serosal tissue (Vser) = fQ * VI | — | Adipose tissue (QAD)f | 6.3 |
Enterocyte tissue (Ven) = (1 − fQ) * VI | — | ||
Liver blood (VLB)d | 3.24 | ||
Liver tissue (VL)e | 6.59 | ||
Rapidly perfused tissue (heart, kidney, lung, brain) (VRP)f | 15.6 | ||
Poorly perfused tissue (muscle, bone, skin) (VPP)f | 210 | ||
Adipose tissue (VAD)f | 21.2 |
^ estimated according to value of fQ, obtained from fitting.
↵a Obtained from Davies and Morris (1993).
↵b Obtained from Peters (2008), based on 40% of intestine volume.
↵c Obtained from Peters (2008), based on 60% of intestine volume.
↵d Obtained from Everett et al. (1956), based on liver weight of 12.1 g, according to Davies and Morris (1993).
↵e Obtained from Gao and Law (2009), based on 60% of organ volume
↵f Obtained from Corley et al. (2005).
↵g Obtained from Gao and Law (2009), based on cardiac output of 89.7 ml·min−1 according to Davies and Morris (1993).