Characteristics of control (CRF) and chronic renal failure (CRF) rats
| Group | CTL | CRF | |
|---|---|---|---|
| Rats (n) | 12 | 13 | |
| Body weight | g | 362.8 ± 25.7 | 371.5 ± 75.9 |
| Serum creatinine | µmol/liter | 59.4 ± 3.1 | 197.9 ± 85.9a |
| Creatinine clearanceb | µl/100 g per min | 244.0 ± 89.9 | 65.5 ± 27.3a |
| Parathyroid hormone | pg/ml | 121.7 ± 26.3 | 1526.8 ± 568.9a |
↵a P < 0.05 versus control group.
↵b Data are the mean ± S.D. Measurements were made at the time of sacrifice. Twenty-four-hour urinary collection was begun the day before. Blood creatinine, and urine creatinine were determined with an Architect C1600 clinical analyzer (Abbott, Saint-Laurent, Canada).