Characteristics of parathyroidectomized (PTX), control (CTL), and chronic renal failure (CRF) rats
| Nephrectomy | (-) | (+) | |||
|---|---|---|---|---|---|
| PTX | (-) | (+) | (-) | (+) | |
| Group | CTL | CTL-PTX | CRF | CRF-PTX | |
| Rats (n) | 13 | 8 | 13 | 11 | |
| Body weight | g | 381.2 ± 20.9 | 432.0 ± 30.5a | 317.9 ± 60.4a | 392.0 ± 43.0 |
| Serum creatinine | µmol/liter | 63.3 ± 5.0 | 66.3 ± 2.4 | 230.5 ± 74.9a | 186.4 ± 61.1a |
| Creatinine clearanceb | µl/100 g per min | 288.4 ± 52.9 | 239.4 ± 36.1 | 56.6 ± 38.1a | 76.0 ± 26.8a |
| PTH | pg/ml | 113.6 ± 36.8 | <29a | 1304.1 ± 914.7a | <29a |
↵a P < 0.05 versus control group.
↵b Data are the mean ± S.D. Measurements were made at the time of sacrifice. Twenty-four hour urinary collection was begun the previous day. Blood creatinine, and urine creatinine were determined with an Architect C1600 clinical analyzer (Abbott, Saint-Laurent, Canada).