TABLE 6

Systemic exposure of metabolites M1 and M2 after an i.p. administration of 1 (10 mg/kg) to control rats or rats pretreated with ABT, allopurinol, or allopurinol + ABT

Area under the curve reported as peak area ratio analyte/IS* h, as no authentic metabolite standards were available. Data represent a mean of n = 2 (± S.E.M). Statistical analyses performed using a two-tailed unpaired t test.