Pharmacokinetic parameters of total radioactivity, dasabuvir, and metabolite M1
Data are presented as means ± S.D.
| Analyte | Cmax | Tmax | AUC0–last | AUC0–∞ | t1/2 |
|---|---|---|---|---|---|
| ngEq/g or ng/ml | h | ngEq/g or ng/ml | h | ||
| Total radioactivity | 1300 ± 586 | 4 ± 0 | 8251 ± 3111 | 9959 ± 3414 | |
| Dasabuvir | 658 ± 252 | 4 ± 0 | 6260 ± 1930 | 6290 ± 1930 | 8.4 ± 3.2 |
| M1 | 267 ± 116 | 3.0 ± 1.2 | 2230 ± 948 | 2280 ± 934 | 6.2 ± 1.3 |
t1/2, half-life.