Mean (%CV) plasma noncompartmental LY2940094 pharmacokinetic parameters by dose after single oral administration to human subjects
| Dose | n | Cmax | Tmaxa | AUC0–28.5 |
|---|---|---|---|---|
| mg | ng/ml | h | h*ng/ml | |
| 4 | 3 | 7.93 (44.2) | 6.00 (13.1) | 63.4 (27.5) |
| 10 | 3 | 22.4 (24.7) | 4.48 (0.8) | 176 (24.0) |
| 20 | 2 | 38.5 NC | 2.32 NC | 316 NC |
| 40 | 4 | 102 (26.2) | 6.00 (12.7) | 811 (16.3) |
AUC0–28.5 = area under the plasma concentration–time curve from 0–28.5 hours after dose administration; NC, not calculated; Tmax = time of maximum concentration.
↵a Median.