Area under the curve (AUC0–12h) ratios of major EPA metabolites relative to EPA in humans following a single oral dose and at steady state.
| Dose | Day | EPA | M9 | M11 | M12 |
|---|---|---|---|---|---|
| 50 mg BID | 1 | 1 | 8.2 | NC | NC |
| 10 | 1 | 8.1 | 0.3 | 0.8 |
NC, Not calculable because most plasma concentrations were below the lower limit of quantitation.