TABLE 2 

In vivo formation of M11 and M12 in mice given EPA with and without antibiotic or ABT pretreatment.

Dose GroupAUC0-6h Ratio Relative to EPA
EPAM11M12
Control1.0000.2600.107
Ciprofloxacin pretreatment1.0000.1190.044
ABT pretreatment1.0000.3720.017
AUC0-6h ratio relative to M11
 Control1.0000.411
 Ciprofloxacin pretreatment1.0000.372
 ABT pretreatment1.0000.045