Transporter protein expression in the human kidney cortex
Data are presented as means ± S.D. given in picomoles per milligram of membrane protein (N = 41).
| Transporter | Protein Expression | Percent Coefficient of Variation |
|---|---|---|
| Uptake | ||
| OAT1 | 5.33 ± 1.88 | 35.3 |
| OAT2 | 0.93 ± 0.32 | 34.6 |
| OAT3 | 3.50 ± 1.55 | 44.3 |
| OAT4 | 0.52 ± 0.23 | 44.5 |
| OCT2 | 7.42 ± 2.84 | 38.3 |
| OCTN1 | 1.27 ± 0.59 | 46.1 |
| OCTN2 | 0.57 ± 0.24 | 41.2 |
| SGLT2 | 3.67 ± 1.86 | 50.6 |
| Efflux | ||
| P-gp | 2.09 ± 0.82 | 39.3 |
| BCRP | < LLOQ | |
| MRP2 | 1.35 ± 0.63 | 46.4 |
| MRP4 | 0.91 ± 0.64 | 70.7 |
| MATE1 | 5.06 ± 2.27 | 45.0 |
| MATE2-K | < LLOQ |