Lot-to-lot variation (%CV) of HepatoCells versus primary human hepatocytes in induction response
The n in parentheses indicates number of lots used in the study.
| Parameters | Lot-to-Lot Variation (%CV) | |
|---|---|---|
| HepatoCells | Primary Human Hepatocytes | |
| CYP3A fourfold induction | 12% (n = 6) | 94% (n = 15) |
| CYP1A twofold induction | 15% (n = 3) | 74% (n = 15) |
| CYP2B sixfold induction | 12% (n = 3) | 100% (n = 15) |