TABLE 5

Transport kinetics of [³H]cefadroxil uptake in P. pastoris cells expressing different mammalian PEPT2 genes

Parameters are expressed as mean ± S.E. (n = 3). Following vector subtraction, the data were fit to a Michaelis-Menten equation using a weighting factor of unity. Cefadroxil concentrations ranged from 1 to 250 μΜ. Statistical analyses were performed using one-way analysis of variance followed by Tukey’s test. Parameters with common capital letters (i.e., A, B, or C) were not significantly different between genotypes.