TABLE 2

Protein expression of BCRP1 in membrane extracts and corrected ERs of dantrolene, daidzein, genistein, and prazosin across MDCKII monolayers transduced with varying titers of BacMam2-Bcrp1 viruses

Protein Level of BCRP1^{^a}	Corrected ER^{^b}
Protein Level of BCRP1^{^a}	Dantrolene	Daidzein	Genistein	Prazosin^{^c}
fmol/µg⋅protein
0	0.79 ± 0.27	1.07 ± 0.23	0.62 ± 0.17	0.71 ± 0.20
11.5	1.47 ± 0.24	2.62 ± 0.20	3.21 ± 0.47	2.12 ± 0.32
36.5	2.89 ± 0.69	4.07 ± 0.82	3.37 ± 0.97	2.95 ± 0.67
65.7	4.10 ± 1.06	6.31 ± 1.82	4.50 ± 0.77	3.89 ± 0.51
232	4.51 ± 1.54	11.0 ± 3.1	6.71 ± 1.92	5.11 ± 1.14
342	6.42 ± 1.75	9.66 ± 1.34	9.26 ± 1.66	7.94 ± 1.44

↵^a Protein levels are the mean value of duplicate measurements.
↵^b Data are presented as the mean ± S.D. from three individual transwell assays.
↵^c One micromolar of LY335979 was included in the transport medium of prazosin.