Lot Number | Activity (pmol/min/million Enterocytes) | |||||||
---|---|---|---|---|---|---|---|---|
CYP2C9 | CYP2C19 | CYP3A4M | CYP3A4T | CYP2J2 | CES2 | UGT | SULT | |
HE3005 | 1.68 | 0.56 | 2.67 | ND | 1.2 | 0.23 | 8.38 | 8.72 |
HE3006 | 0.59 | 0.29 | 0.13 | 6.23 | 0.73 | 0.33 | 2.3 | 2.04 |
HE3007 | 0.91 | 0.39 | 0.99 | 22.7 | 0.57 | 0.46 | 3.08 | 4.04 |
HE3008 | 0.46 | 0.68 | 0.87 | NA | 0.33 | 0.55 | 1.8 | 1.79 |
HE3009 | 1.18 | 0.35 | 0.72 | 32.1 | 0.25 | 0.6 | 4.32 | 7.78 |
HE3010 | 1.21 | 0.62 | 0.46 | 17.5 | 0.99 | 0.41 | 2.56 | 3.32 |
HE3011 | 0.03 | 0.01 | 0.09 | 2.6 | 0.33 | 0.29 | 1.01 | 1.7 |
HE3014 | 0.44 | 0.11 | 0.4 | 8.2 | 1.18 | 0.17 | 3.55 | 2.66 |
HE3015 | 2.5 | 0.49 | 2.55 | ND | 0.95 | 0.51 | 7.33 | 5.23 |
HE3016 | 2.05 | 1.08 | 0.99 | 26.7 | 0.93 | 0.34 | 5.71 | 4.13 |
HE3019 | 0.24 | 0.11 | 0.3 | 5.27 | 0.26 | 0.3 | 1.47 | 1.89 |
HE3020 | 0.31 | 0.14 | 0.49 | 12.9 | 0.58 | 0.59 | 5.83 | 1.84 |
HE3021 | 0.2 | 0.06 | 0.17 | 2.97 | 0.19 | 0.08 | 1.49 | 1.64 |
HE3027 | 2.02 | 0.31 | 0.68 | 25.9 | 0.76 | 0.19 | 3.68 | 2.69 |
HE3028 | 0.68 | 0.21 | 0.82 | 26 | 0.71 | 0.3 | 3.84 | 9.02 |
HE3029 | 0.86 | 0.12 | 0.59 | 12.1 | 0.76 | 0.08 | 6.55 | 3.65 |
HE3030 | 0.26 | 0.28 | 0.29 | 14.9 | 0.32 | 0.05 | 15 | 8.3 |
HE3031 | 0.34 | 0.09 | 0.16 | 2.95 | 0.49 | 0.18 | 1.6 | 0.79 |
HE3032 | 1.84 | 0.81 | 1.3 | 43.4 | 0.82 | 0.24 | 5.9 | 4.5 |
HE3033 | 2.11 | 1.13 | 1.03 | 28.4 | 0.7 | 0.11 | 29.6 | 14.2 |
HE3034 | 7.93 | 0.71 | 4.35 | 45.2 | 1.98 | 0.12 | 122.6 | 8.24 |
HE3040 | 0.96 | 0.78 | 1.00 | 32.30 | 0.30 | 0.18 | 23.80 | 22.00 |
HE3042 | 0.23 | 0.03 | 1.66 | 31.20 | 1.06 | 0.06 | 74.20 | 8.98 |
HE3043 | 1.39 | 0.21 | 0.62 | 18.80 | 0.55 | 0.23 | 9.13 | 9.00 |
Mean | 1.27 | 0.40 | 0.97 | 19.92 | 0.71 | 0.28 | 14.36 | 5.76 |
S.D. | 1.59 | 0.33 | 0.99 | 12.99 | 0.41 | 0.17 | 27.74 | 4.88 |
NA, not applicable; ND, not determined.