TABLE 4 

Relative AUC exposure levels of MMB and metabolites in rat, dog, and human AUC pooled plasma samples at steady state at the corresponding NOAEL dose level in rat and dog

AnalyteDog to HumanRat to Human
MMB1.213.1
M21NO0.22
M193.211.5
  • NO, metabolite peak not observed; NOAEL, no-observed-adverse-effect level.