TABLE 3

Summary of peptides that underwent other significant biotransformation

The mass difference of each PTM was shown in the peptide sequence: deamidation (+0.98), carbamidomethylation (+57.02), and dimethylation (+28.03).

Native PeptidesModified Peptides% Modified
BiotransformedControl
TVLHQDWLNGKTVLHQDWLN(+0.98)GK45.536.6
VVSVLTVLHQDWLNGKVVSVLTVLHQDWLN(+0.98)GK76.339.6
C(+57.02)PAPELLGGPSVFLFPPKPKC(+57.02)(+28.03)PAPELLGGPSVFLFPPKPK55.544.3
EEQYNSTYREEQYN(+0.98)STYR4210.5
FNWYVDGVEVHNAKFNWYVDGVEVHN(+0.98)AK3.34.8
HQDWLNGKHQDWLN(+0.98)GK6451
IC(+57.02)NVNHKPSNTKIC(+57.02)NVN(+0.98)HKPSNTK6.40