TABLE 3

GQ-11 metabolites using ultraperformance LC coupled to hybrid quadrupole-time of flight after human and rat liver microsome incubation

Plus (+) sign indicates presence of the metabolite.

MetabolitesM + HError RetentionTimeProduct IonsRLMsHLMs
m/zppmminm/z
M1365.0944−4.34.04105, 132+
M2365.0948−3.24.20121, 173, 319, 347++
M3365.09600.14.87105, 189, 245, 273, 294, 322++
M4365.09641.24.97105, 189, 245, 273, 294, 322++
M5365.09774.85.23105, 189, 245, 273, 294, 322++