TABLE 2

CYP2J gene expressions in human and other mammalian tissues

Expression is quantified, whereby (+) is low expression, (++) is moderate expression and (+++) is high expression. Within the heart, human CYP2J2 has the highest level of RNA and protein expression. Rat CYP2J3 has high levels of protein and mouse CYP2J11 has high RNA expression in the heart, indicating that there are often discrepancies between RNA and protein expression in different homologs.

HumanMouseMonkeyRat
2J22J52J62J82J92J112J122J132J22J32J4
Liver+++++++
RNA++++++++
Protein+++++++++
Heart+++
RNA+++++++
Protein+++++++
Small intestine++++++++++
RNA+++++
Protein++++
Lung+++++++
RNA++
Protein++
Kidney+++++++
RNA+++++++++++
Protein+++++++++++
Brain++++++
RNA+++++
Protein++++++
Pancreas+++
RNA+
Protein+
Stomach+
RNA+
Protein+
Spleen+++
RNA
Protein
Skeletal muscle++
RNA
Protein
  • Adapted from Xu et al. (2013).