Permeability coefficient of six corneal models
Each value represents the mean ± S.D. of three independent experiments.
| Type of Model | Permeability Coefficient | |||||
|---|---|---|---|---|---|---|
| Cyanocobalamin | FD-4 | FD-10 | FD-20 | FD-40 | ||
| ×10−6 cm/s | ||||||
| Acellular model | BM | 9.38 ± 0.47 | 4.22 ± 0.18 | 1.20 ± 0.31 | 0.46 ± 0.06 | 0.12 ± 0.002 |
| AS | 4.45 ± 0.32 | 1.46 ± 0.14 | 0.81 ± 0.11 | 0.24 ± 0.03 | 0.17 ± 0.03 | |
| Culture model | CEpi | 0.82 ± 0.097 | 0.36 ± 0.01 | 0.31 ± 0.02 | 0.36 ± 0.06 | 0.054 ± 0.01 |
| CEpi-Endo | Not detected | 0.25 ± 0.04 | 0.13 ± 0.02 | 0.084 ± 0.01 | 0.050 ± 0.01 | |
| CEpi-AS | Not detected | 0.14 ± 0.06 | 0.046 ± 0.07 | 0.009 ± 0.002 | 0.017 ± 0.009 | |
| CEpi-AS -Endo | Not detected | 0.033 ± 0.02 | 0.019 ± 0.01 | 0.016 ± 0.005 | 0.033 ± 0.028 | |