TABLE 2

Lesinurad atropisomer urine pharmacokinetic parameters (geometric mean and 95% confidence interval)

The P values were determined using a paired t test. The fraction excreted in urine and CLr values for each atropisomer were calculated using one-half of the racemate dose based on the fact that the racemate exists as a 50:50 mixture of two atropisomers and absorption of lesinurad was assumed to be nonstereoselective.