TABLE 2

Michaelis-Menten kinetic parameters for the oxidative deamination of benzylamine in human sources of VAP-1

Test SystemKMVmax
µMnmol/min/mg protein
rhVAP-1a56.6 ± 32.71040 ± 506
hUCM80.03.09
hAMa78.9 ± 33.865.6 ± 4.64
hPb75.2 ± 4.560.467 ± 0.024 (17.6 nmol/ml/h)

  • ↵a Mean ± S.D. of n = 4 different occasions, each in triplicate.

  • ↵b Mean ± S.D. of n = 3 different occasions, two in duplicate and one in triplicate.