TABLE 3

Correlations of in vitro emixustat oxidative deamination metabolism, benzylamine deamination, and VAP-1 levels

CorrelationSpearmanPearson
rTwo-Tailed PrTwo-Tailed P
hUCM emixustat deamination vs. hUCM BA deamination0.705<0.0010.7360.0018
hUCM emixustat deamination vs. hUCM VAP-1 levels0.827<0.0010.886<0.0001
hUCM BA deamination vs. hUCM VAP-1 levels0.639<0.0050.627<0.005
hAM emixustat deamination vs. hAM BA deamination0.794<0.000010.823<0.00001
hAM emixustat deamination vs. hAM VAP-1 levels0.789<0.000010.7320.0002
hAM BA deamination vs. hAM VAP-1 levels0.5430.0130.5680.009
hP emixustat deamination vs. hP BA deamination0.922<0.000010.8210.0002
hP emixustat deamination vs. hP VAP-1 levels0.874<0.000010.7640.0009
hP BA deamination vs. hP VAP-1 levels0.911<0.000010.913<0.00001
hAM emixustat deamination vs. hP emixustat deamination0.5820.0250.6290.012
hAM emixustat deamination vs. hP BA deamination0.4440.0690.5310.023
hAM emixustat deamination vs. hP VAP-10.4860.0410.4770.045