TABLE 4

The effect of IC50 values of fasiglifam and fasiglifam-G on hepatobiliary transporters

SpeciesIC50 (μmol/l)
Mrp2Bsep
FasiglifamFasiglifam-GFasiglifamFasiglifam-G
Rat—2.920.682.5
Dog—5.116.118.2

  • —, not determined.