TABLE 1

Concentrations of radioactivity in the plasma and liver after administration of a single oral dose of [14C]fasiglifam in rats and dogs

Data were obtained from one animal for each collection time.

SpeciesDoseTimeConcentration of Radioactivity (ยตg Eq/ml or g)
PlasmaLiver
mg/kgh
Rat214.9818.1
283.3213.8
2001237275
2008352341
Dog225.0410.6
281.845.08
2002315179
200839.055.3