TABLE 2

The Spearman correlation analysis of intratumoral payload exposure (payload AUC) vs. TGI%, total antibody exposure (Tab AUC) vs. TGI%, and intratumoral payload exposure (payload AUC) vs. total antibody exposure (Tab AUC)

	TGI vs. Intratumoral Payload AUC		TGI vs. Tab AUC		Intratumoral Payload AUC vs. Tab AUC
	Correlation Coefficient	Sig (Two-Tailed)	Correlation Coefficient	Sig (Two-Tailed)	Correlation Coefficient	Sig (Two-Tailed)
HER2-PBD ADCs A1-A4 (in Fig. 2, B and C)	0.800	0.200	0.800	0.300	0.443	0.553
HER2-PBD ADCs A1-A4 (in Fig. 2, B and C)^a	1.000^{^a}	0.000^*
CD22-MMAE ADCs B1-B4 (in Fig. 2, E and F)	0.795	0.010^*	0.383	0.308	0	1.0
CD22-DMx ADCs C1-C8 (in Fig. 2, H and I)	0.900	0.037^*	0.100	0.873	0.300	0.624

Sig, significance.
↵* P < 0.05.
↵^a When data of conjugate A2 was corrected by S.D.