Effects of different matrices on the binding of C225 to the sensor surface (mean ± S.D., n = 3)
| Concentration of C225 (0.4 μg/ml) | Observed Concentration (μg/ml, Mean ± S.D.) | Precision (%) | Accuracy (%) |
|---|---|---|---|
| 50% human serum | 0.432 ± 0.027 | 6.25 | 108.0 |
| 50% Sprague Dawley rat serum | 0.442 ± 0.057 | 12.93 | 110.5 |
| 20% monkey serum containing 0.4 μg/ml chimeric recombinant anti-CD20 monoclonal antibody | 0.424 ± 0.021 | 4.84 | 106.0 |
| 20% monkey serum containing 0.4 μg/ml human γ-globulin | 0.439 ± 0.064 | 14.47 | 109.8 |
| 20% monkey serum containing 0.4 μg/ml chimeric recombinant her 2 antibody | 0.458 ± 0.040 | 8.64 | 114.5 |