% Sample Radioactivity (pg equivalents [14C]nemiralisib/g) | ||
---|---|---|
Plasma | ||
ID | Intravenous | Oral |
0–24 h | 0–24 h | |
P (nemiralisib)a | 87.6 (47.3) | 76.3 (511) |
M1(GSK2330979) and/or M9 | 8.4 (4.6) | 10.0 (66.7) |
Total radioactive material assigned % (pg equivalents [14C]nemiralisib/g) | 96.0 (51.9) | 86.3 (578) |
Total pg equivalents [14C]nemiralisib/g in pool | 54.0 | 670 |
↵a Identified by LC-MS, all other peaks identified by comparison of relative retention times to pre-existing data from in vitro human hepatocytes.