TABLE 2

Rate constant outputs from two numerical TDI models for HLM data

Each model was tested in the presence and absence of the irreversible inactivation event (k9). Dashes indiciate an absence of the corresponding rate constant from the model.

Rate ConstantEMQI
IrreversibleReversibleIrreversibleReversible
min−1
k36.291 ± 0.1296.270 ± 0.1126.294 ± 0.1186.270 ± 0.126
k60.3800 ± 0.06420.3411 ± 0.00240.3833 ± 0.06340.3425 ± 0.0359
k70.0538 ± 0.01740.0406 ± 0.00260.0545 ± 0.01760.0406 ± 0.0049
k80.0118 ± 0.01300.0102 ± 0.00200.0126 ± 0.01340.0103 ± 0.0020
k90.0103 ± 0.00200.0104 ± 0.0013