Correlation coefficients (Spearman’s rho) between the CLint,u values of P450 isoforms in human liver microsomes
| CYP1A2 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | |
|---|---|---|---|---|---|---|
| CYP2B6 | 0.51* | |||||
| CYP2C8 | 0.09 | 0.13 | ||||
| CYP2C9 | −0.22 | −0.07 | 0.32 | |||
| CYP2C19 | 0.02 | 0.24 | −0.55 | 0.02 | ||
| CYP2D6 | 0.58** | 0.60** | 0.25 | −0.26 | −0.30 | |
| CYP3A | 0.68*** | 0.67** | 0.36 | −0.15 | −0.36 | 0.47* |
↵*P < 0.05; **P < 0.01; ***P < 0.001.