TABLE 2

Final parameter estimates from the model fitting

Hepatocyte lotCLuptakeCLint,BLCLint,bileKflux
(ml/min)/g liver (CV%)min−1(CV%)
Lot 10.69 (15%)0.16 (68%)0.18 (47%)0.31 (41%)
Lot 21.2 (9%)0.17 (19%)0.083 (35%)0.21 (22%)
Lot 30.98 (9%)0.21 (14%)0.073 (28%)0.17 (22%)
Mean ± S.D.0.96 ± 0.260.18 ± 0.030.11 ± 0.060.23 ± 0.07