TABLE 1

Non–small cell lung cancer patient information Patient information is summarized in the table. In subject PTX-6, paclitaxel administration was discontinued due to paclitaxel allergy.Alb, albumin; AGP, α1-acid glycoprotein; AST, aspartate aminotransferase; ALT, alanine aminotransferase;LDH, lactate dehydrogenase; ALP, alkaline phosphatase; T-Bil, total bilirubins; D-Bil, direct bilirubins; SCr, serum creatinine; eGFR,estimated glemerular filtration rate; M, male, F, female; —, no comlication

IDSexAgeHeightb.wt.OATP1B1 haplotypeAlbAGPASTALTLDHALPT-BilD-BilSCreGFRComplicationsMedications
ycmkgg/dlmg/dlIU/lmg/dlmL/min
PTX-1M74159.554.3*1b/*1b4.352.037212003541.30.10.8171.0Alcoholic hepatitis, hyperuricemia, allergic rhinitisLivact, Feburic, Xyzal
PTX-2F75161.556.9*1a/*1b4.065.021141802160.9<0.10.6863.3Dyslipidemia, osteoporosisLipitor, Edirol, Protecadin
PTX-3M5816973.2*1b/*1b3.3144.032242692160.5<0.10.8968.7Hypertension, atrial fibrillationTenormin, Atelec, Olmetec, Xarelto, Tambocor, Eperisone, alprazolam
PTX-4M57164.553.5*1b/*154.273.01261151351.60.10.7287.1DyslipidemiaBezatol, Urso, Pinellia Heart-Purging Decoction, Clostridium butyricum
PTX-5M4816958.6*1b/*154.076.028251620.90.10.8972.9HypertensionPreminent, Depas
PTX-7M6616563*1b/*153.984.035492943050.50.11.0356.4Hypertension, anginaHerbesser R, valsartan
PTX-8M67163.544.6*1a/*1b3.4154.01982890.70.10.6987.1HypertensionIrbetan, famotidine
PTX-9M5717172*1a/*1b4.496.018132192190.80.10.7682.1HyperuricemiaAlositol, Takecab, Rebamipide
PTX-10M6817063.9*1b/*1b3.9188.01693444160.4<0.11.1549.6Reflux esophagitisNexium
PTX-11M5216053*1a/*1b3.7156.016101562250.5<0.10.8277.6Takecab, loxoprofen, Tapenta, Etizolam, Rivotril